The 1st Project
on LAVO Protocol
Project Name: EXOSOMES
Token: $EXO
Total Supply: 10B
Chain: BSC
What is EXO
EXO is LAVO’s first ecosystem project, focusing on exosome-based
rejuvenation technology and data-driven anti-aging applications
The Challange
Our Solution
A Trillion-Dollar Convergence
Sources:
- Grand View Research. “Exosomes Market Size, Share & Trends Analysis Report By Application (Therapeutics,Diagnostics), By Product (Services, Kits & Reagents), By End-use, By Region, And Segment Forecasts, 2024 – 2030.”
- Global Market Insights. “Anti-Aging Market Size By Product, By Demography, By End-Use, Industry Analysis Report, Regional Outlook, Growth Potential, Price Trends, Competitive Market Share & Forecast, 2024 – 2032.”
- Precedence Research. “Artificial Intelligence in Biotechnology Market Size, Report 2022-2032.”
ExoBiome Scientific Platform
& Biological Rationale
ExoBiome is a proprietary biotechnology platform that produces standardized, skin-compatible actives by combining microbiota-derived Extracellular Vesicles (EVs) and bacterial lysates.
The "Dual-Signal" Approach
• Bacterial Lysates: Provide structural cell-wall
fragments and metabolites that directly stimulate
keratinocyte defense and reinforce the physical skin barrier.
• Extracellular Vesicles (30–200 nm): Act as nanosized biological messengers (exosomes) that carry proteins, lipids, and nucleic acids to facilitate deep cellular communication and tissue repair.
• Extracellular Vesicles (30–200 nm): Act as nanosized biological messengers (exosomes) that carry proteins, lipids, and nucleic acids to facilitate deep cellular communication and tissue repair.
Scientific Rationale:
By recombining both lysate and EV fractions, the platform mimics the skin’s native microbiota communication network, supporting immune homeostasis and lipid metabolism.
Biological Action:
• Barrier Defense: Prevents pathogen colonization and
regulates natural moisturizing factors.
• Immune Modulation: Communicates with immune cells to reduce chronic low-grade inflammation and sensitivity.
• Regenerative Signaling: Delivers microbiome-supporting signals that are more targeted than traditional peptides or growth factors.
• Immune Modulation: Communicates with immune cells to reduce chronic low-grade inflammation and sensitivity.
• Regenerative Signaling: Delivers microbiome-supporting signals that are more targeted than traditional peptides or growth factors.
Product Technical Methodology
& Quality Control
A controlled, five-step process designed for high-yield,
medical-grade standardization.
1. Strain Selection
Beneficial commensal species
(e.g., Lactobacillus, Staphylococcus epidermidis)
are screened for specific anti-inflammatory signaling
and metabolite profiles.
2. Optimized Fermentation
Oxygen-controlled batch cultivation maximizes the yield
of Extracellular Vesicles and ensures metabolic
consistency across batches.
3. Dual-Phase Extraction
• Lysate Fraction: Controlled cell disruption to recover intracellular metabolites.
• EV Fraction: Isolated via TFF and chromatography to preserve vesicle integrity.
4. Standardization & QC
Every batch is quantified using specific protein and
lipid markers (e.g., CD63, GroEL) and tested for
microbial safety and endotoxin limits.
5. Formulation Integration
The final active is delivered as a stable liquid or
freeze-dried concentrate, optimized for a 0.5–3.0%
inclusion rate in cosmetic and clinical applications.
- LavoProtocol
- enquiry@lavoprotocol.io
- @LAVOPROTOCOL
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